Compound record

Goserelin

ICI 118630; D-Ser(tBu)6-Azagly10-GnRH

Linear C-terminal amidation D-amino acid N-terminal pyroglutamate Unusual amino acid

Sequence

pEHWSY(dSer(tBu))LRP-Azagly-NH2

EHWSYSLRPX

Length 10 residues

Formula C59H84N18O14 elemental composition

Molecular weight 1,269.41 g/mol · average mass

CAS number 65807-02-5 registry ID

PubChem CID 5311128 PubChem ID

Length counts residues; formula and mass are the stored free-base values from cited sources; CAS and PubChem identify the substance in public registries. More detail: length & peptide bonds, molecular weight

Structure & modifications

Linear peptidomimetic. Azaglycine is not a canonical residue.

Notes

Goserelin is a decapeptide GnRH agonist with O-tert-butyl-D-serine at position 6 and an azaglycine amide at position 10.

Azaglycine (NH-NH-CONH2) is non-canonical — the 1-letter X is a placeholder. Pyroglutamate at the N-terminus is retained.

	Leuprolide	Goserelin
Length	9	10
Position 6	D-Leu	D-Ser(tBu)
C-terminus	Pro-NHEt	Azagly-NH2
CAS	53714-56-0	65807-02-5

These are not interchangeable identities. PubChem CID for goserelin: 5311128.

Primary-source references

PubChem CID 5311128 — goserelin
CAS 65807-02-5

Browse compounds Nulife catalog View on PubChem