Compound record
Leu-enkephalin
[Leu5]enkephalin
Sequence
YGGFL
YGGFL
Length
5
residues
Formula
C28H37N5O7
elemental composition
Molecular weight
555.63
g/mol · average mass
CAS number
58822-25-6
registry ID
PubChem CID
439240
PubChem ID
Length counts residues; formula and mass are the stored free-base values from cited sources; CAS and PubChem identify the substance in public registries. More detail: length & peptide bonds, molecular weight
Structure & modifications
Linear pentapeptide, unmodified termini.
Notes
Leu-enkephalin (YGGFL) differs from Met-enkephalin only at residue 5. Both share the opioid YGGF motif and free termini.
When chromatography or mass data “almost match” Met-enkephalin, check position 5 and the CAS pair first — swapping Met/Leu is a frequent mix-up.
| Property | Value |
|---|---|
| Topology | Linear, unmodified |
| Formula / MW | C28H37N5O7 · 555.63 |
| CAS / PubChem | 58822-25-6 / 439240 |
Primary-source references
- PubChem CID 439240 — Leu-enkephalin
- Hughes J. et al. Nature 1975, 258, 577–580.