Compound record

Teriparatide

PTH(1–34); human parathyroid hormone 1–34

Linear

Sequence

SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF

SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF

Length 34 residues
Formula C181H291N55O51S2 elemental composition
Molecular weight 4,117.72 g/mol · average mass
CAS number 52232-67-4 registry ID
PubChem CID 16129656 PubChem ID

Length counts residues; formula and mass are the stored free-base values from cited sources; CAS and PubChem identify the substance in public registries. More detail: length & peptide bonds, molecular weight

Structure & modifications

Linear 34-mer with two methionines. Amphipathic helix in the receptor-bound state.

Notes

Teriparatide is recombinant human PTH(1–34) — the N-terminal fragment that retains PTH1-receptor agonism of full-length PTH(1–84).

It is linear and unmodified, with two methionines that can oxidize during careless handling. Amphipathic helix matters for receptor binding but is not a covalent classification flag.

PropertyValue
Length34
Disulfide / amideNone on this record
CAS / PubChem52232-67-4 / 16129656
PrecursorUniProt P01270

Full-length PTH(1–84) and other truncations are different entities — do not reuse this CAS.

Primary-source references

  • PubChem CID 16129656 — teriparatide
  • UniProt P01270 (parathyroid hormone)
  • Potts J.T. et al. Synthesis of a biologically active N-terminal tetratriacontapeptide of parathyroid hormone. Proc. Natl. Acad. Sci. USA 1971.

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