Compound record

Lanreotide

BIM-23014; lanreotide acetate (salt form not listed here)

Cyclic C-terminal amidation D-amino acid Disulfide bridge Unusual amino acid

Sequence

dNal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 (Cys2–Cys7 disulfide)

XCYWKVCT

Length 8 residues
Formula C54H69N11O10S2 elemental composition
Molecular weight 1,096.32 g/mol · average mass
CAS number 108736-35-2 registry ID
PubChem CID 6918013 PubChem ID

Length counts residues; formula and mass are the stored free-base values from cited sources; CAS and PubChem identify the substance in public registries. More detail: length & peptide bonds, molecular weight

Structure & modifications

X in the 1-letter field stands for D-2-naphthylalanine, which is not a canonical residue.

Notes

Lanreotide (BIM-23014) is a disulfide-cyclized somatostatin octapeptide related to octreotide but different at both termini.

OctreotideLanreotide
Position 1D-PheD-2-Nal (X in 1-letter)
C-terminusThreoninolThr-NH2
DisulfideCys2–Cys7Cys2–Cys7
CAS83150-76-9108736-35-2

Display notation is mandatory because naphthylalanine is non-canonical. Modification tags include disulfide, D-amino acid, C-terminal amidation, and unusual amino acid.

Acetate salts are common in products and may carry different registry numbers than the free base listed here (PubChem CID 6918013).

Primary-source references

  • PubChem CID 6918013 — lanreotide
  • CAS 108736-35-2

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