Compound record
Arginine vasopressin
Argipressin; AVP; ADH; 8-L-arginine vasopressin
Sequence
CYFQNCPRG-NH2 (disulfide Cys1–Cys6)
CYFQNCPRG
Length counts residues; formula and mass are the stored free-base values from cited sources; CAS and PubChem identify the substance in public registries. More detail: length & peptide bonds, molecular weight
Structure & modifications
Tocin-ring architecture homologous to oxytocin; Phe3 and Arg8 distinguish AVP from oxytocin.
Notes
Arginine vasopressin (AVP) — also called argipressin — is the human antidiuretic hormone. It shares oxytocin’s tocin-ring architecture but differs at two decisive positions.
| Position | Oxytocin | AVP (this record) |
|---|---|---|
| 3 | Ile | Phe |
| 8 | Leu | Arg |
| Disulfide | Cys1–Cys6 | Cys1–Cys6 |
| C-terminus | Gly-NH2 | Gly-NH2 |
Those substitutions shift preference toward V1/V2 vasopressin receptors while keeping the intramolecular disulfide and C-terminal amide. Classification remains cyclic.
This entry stores the mature nonapeptide, not the vasopressin–neurophysin 2–copeptin precursor. Compare separately with desmopressin, terlipressin, and atosiban when studying analogue chemistry.
Confirm free-base identity with CAS 113-79-1 and PubChem CID 644077.
Primary-source references
- PubChem CID 644077 — argipressin
- UniProt P01185 (vasopressin-neurophysin 2-copeptin)
- CAS Common Chemistry 113-79-1