Compound record
Eptifibatide
Integrilin (brand; listed only as a synonym); C68-22
Sequence
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 (disulfide Mpr–Cys)
XGDWPC
Length counts residues; formula and mass are the stored free-base values from cited sources; CAS and PubChem identify the substance in public registries. More detail: length & peptide bonds, molecular weight
Structure & modifications
Cyclic heptapeptide with two non-canonical residues (Mpr, homoarginine).
Notes
Eptifibatide is a cyclic heptapeptide GPIIb/IIIa antagonist presenting an RGD-related Har-Gly-Asp turn inside a disulfide-closed ring (from disintegrin design principles).
| Non-canonical piece | Role |
|---|---|
| Mpr (mercaptopropionyl) | N-terminal cap in the disulfide |
| Homoarginine (Har) | RGD-like presentation |
| C-terminal amide | Terminal modification |
Display notation is required; 1-letter placeholders under-represent chemistry. Brand synonyms are cross-references only. CAS 188627-80-7, PubChem 448812.
Primary-source references
- PubChem CID 448812 — eptifibatide
- CAS 188627-80-7
- Scarborough R.M. et al. Design of potent and specific integrin antagonists. J. Biol. Chem. 1993.